Tretiheal 0.05% is a topical cream used to treat acne. Its active ingredient, tretinoin, works by unclogging pores and promoting skin cell turnover. This medication is applied to the affected areas once daily, preferably in the evening. It is essential to use sunscreen during the day when using Tretiheal 0.05% to prevent skin sensitivity and sunburn. Common side effects include redness, peeling, and dryness. It may take several weeks to see improvements in the skin’s condition. If irritation persists, discontinue use and consult a dermatologist.